Peer reviewed study shows Entostat sprayable formulation optimises delivery of synthetic chemistry

Study reiterates growing portfolio of dry and wet formulations enabled by Lean Formulation Technology®
4 January 2017

Winchester, UK – A study, just published demonstrates the ability of Exosect’s proprietary lean formulation technology, to optimise the delivery of synthetic chemistry in a sprayable format. This data adds to the growing number of novel formulations made possible by Exosect’s inert formulation platform, Entostat®, in both dry and wet formats.

The paper, published last month in the proceedings of the 68th International Symposium on Crop Protection, was presented earlier in 2016 by Exosect research Scientist, Kristi Thomas. It documents a breakthrough in the development of Entostat, a dry micro-powder formulation platform, which has been formulated into a sprayable SC format suitable for use in standard spray equipment.

A Suspension Concentrate of Deltamethrin based on the Entostat platform was compared directly with a conventional commercial formulation. Both formulations were applied to Chinese cabbage and their efficacy tested against Plutella xylostella (Diamond Back Moth). The two key findings in this study were that the Entostat formulation facilitated a more targeted delivery and bioefficacy was significantly increased: the amount of chemical adhering to the leaf immediately after spraying was more than doubled, while mortality of the pest 46 days after crop spraying was 20% higher than with the comparable commercial standard.

Earlier in the year, an independent study by Professor Christos Athanassiou at the University of Thessaly, in Greece, was published in the journal Pest Management Science. This study showed that an Entostat formulation of Pirimiphos-methyl in a dry format enabled a fourfold increase in insecticidal efficacy, compared with Actellic, the commercial EC formulation of Pirimiphos-methyl, against a range of stored product beetles.

Added to this is the most recent announcement of the successful delivery of the neonicotinoid, Acetamiprid, as a dry seed treatment application for systemic control of aphids.

Exosect’s Chief Technology Officer, Dr. Aoife Dillon, comments,

“A key challenge for the agrochemical industry is to improve the environmental profile of registered Active Ingredients while new chemistry comes through the development pipeline. In the last twelve months we have experienced significant breakthroughs in the delivery of synthetic chemistry in a range of formats which would enable differentiation and patent extension. We continue to focus on improving the formulation and delivery of both synthetic chemistry and biological organisms and look forward to announcing further advances in both dry and sprayable formulations in the coming months.”

Entostat is a proprietary micro-powder, based on natural and/or synthetic waxes and has electrostatic properties. It is a formulation delivery platform for a wide range of biological and synthetic active ingredients. The constituents of Entostat are listed on FIFRA’s 25(b) list of inert ingredients that can be used in pesticide products that are exempt from regulation.

The electrostatic properties of Entostat enable adhesion of active ingredient to a range of surfaces including grains, seeds and pellets, insects, foliage and building structures. The platform can assist with a range of formulation challenges such as increasing biological loading and improving the shelf life of biological material as well as reducing the concentration of synthetic active ingredients.

Exosect out-licenses its intellectual property to enable others to develop a differentiated product portfolio.

Exosect news link: https://www.exosect.com/news/news-detail.aspx?id=109